Clarithromycin is part of the class of drugs known as macrolide antibiotics. This medication is employed to combat infections caused by specific bacteria. It does this by blocking or halting the expansion of the bacteria that cause certain infections. Clarithromycin can be prescribed to those suffering from sinus-related infections and ear problems pneumonia, bronchitis, and skin diseases such as the cellulitis and impetigo.
Clarithromycin can also be used to treat and prevent certain diseases (mycobacterium Avium complex or MAC) which are related to human immunodeficiency (HIV) disease. Clarithromycin can be utilized together with other drugs to eradicate H. Pylori, which is the bacteria that causes stomach ulcers.
The medication is available under multiple brand names , and/or in various forms. The brand name that is used for this medication might not be available in all the forms or be approved for all conditions listed in this article. Also, certain types of this medication might not be appropriate for all ailments discussed here.
Your physician may have recommended the medication for other conditions than those described in these articles about drugs. If you’ve not talked to your doctor about this or aren’t sure what the reason is behind using this medicine, talk with your physician. Don’t discontinue taking this medication without consulting with your doctor.
Don’t give this medication to anyone other than yourself even if they are suffering from similar symptoms to those you have. It could be dangerous for patients to take this medication if the medical professional hasn’t recommended the medication.
What form(s) do this medicine comes in?
250 mg
Every oval yellow film-coated tablet on one side with “M” to one of the sides, has 250 mg clarithromycin. Nonmedicinal ingredients include cellulosic polymers such as croscarmellose sodium D&C yellow No. 10, magnesium Stearate povidone (pregelatinized starch) propylene glycol, silicon dioxide, sorbic acid the sorbitan monooleate, stearic acids and titanium dioxide and vanillin. This medication is not a source of tartrazine.
500 mg
Every oval light yellow film-coated tablet, by a “M” in one corner, is packed with 500 milligrams of clarithromycin. Nonmedicinal ingredients: cellulosic Polymers as well as colloidal silicon dioxide Croscarmellose sodium D&C Yellow No. 10, magnesium Stearate propylene glycol, povidone sorbitan monooleate, sorbic acid titanium dioxide, vanillin. This medicine does not contain tartrazine.
How do I take this medicine?
Adults The recommended dose for adults of clarithromycin tablets ranges from 250 mg-500 mg twice every day (every for 12 hours) for 7 to 14 days according to the disease being treated.
The dosage for adults recommended for the extended-release version of clarithromycin is 1000 mg (2 tablets) every day for 5 to 14 days depending on the condition treated.
To treat and prevent the development of MAC The usual dosage for clarithromycin is 500 milligrams twice per day. If used in conjunction with other drugs to eliminate H. Pylori the recommended dose for clarithromycin will be 500 mg a day for 10 days.
For children: the recommended daily dosage in children’s bodies is 15 mg per kg (to 1000 mg daily). The total daily dose must be divided into two equal doses that are administered at intervals of 12 hours. The typical duration of treatment is between 5 and 10 days, dependent on the disease being addressed. To treat and prevent the occurrence of MAC the standard dosage of clarithromycin is 7.5 milligrams per kg of body mass twice a day (up up to 500 mg twice a day).
If your child is taking the clarithromycin oral solution make use of an oral syringe determine the dosage of each liquid. It provides an accurate measurement than the standard teaspoons.
Clarithromycin tablet and clarithromycin suspension (given every two days) can be taken without or with food. The combination of this medication with food can cause less stomach upset.
The extended-release tablets of clarithromycin should be taken along with food. The tablets should be swallowed whole , and not crushed or broken.
Take your time with this medication, even if are beginning to start feeling better.
Numerous factors can alter the dosage of medication is required by a patient including body weight, medical conditions, and medication. If your physician has suggested an amount that is different than the one listed below don’t alter the way you’re taking the medication , without consulting with your physician.
It is crucial to use this medication as directed by your physician. If you are unable to take a dose, you should take it as quickly as you can and follow your normal schedule. If it’s getting close for your next dose do not take any missed doses and proceed following your usual dosing regimen. Don’t take a second dose to cover an absence. If you’re unsure what you should do after missing the dose, call your physician or pharmacist for assistance.
Keep clarithromycin tablets in a cool, dry temperature. Protect them from moisture and light as well as keep them away from reach of young children.
Clarithromycin oral suspension should be stored at ambient temperature. Keep the bottle tightly shut and shielded from light. Do not freeze. Any oral suspension that is not used is best discarded within 14 days. Rinse the oral syringe that measures doses between each use. Don’t store the suspension within the syringe.
Don’t dispose of medicines in water (e.g. in the sink, or the bathroom) as well as in the household waste. Ask your pharmacist about how to dispose of medicines which are no longer required or are expiring.
Who should not be taking this medicine?
Don’t take clarithromycin if:
are sensitive to clarithromycin, or any other ingredient in this medication
Are allergic to macrolide antibiotics in other forms, like azithromycin or erythromycin.
Patients have experienced the condition of jaundice (yellowing of the eyes or skin) or liver issues that are caused by taking clarithromycin.
suffer from severe liver failure along with diminished kidney function.
are suffering from or have experienced QT lengthening (an unusual electrical pattern in the heart) or an abnormal heart rhythm.
suffer from untreated hypokalemia untreated (low potassium levels)) as well as hypermagnesemia (low concentrations of magnesium in blood)
Are taking any of these medications:
astemizole
Cisapride
colchicine
domperidone
ergot alkaloids (e.g., dihydroergotamine, ergonovine, ergotamine, methylergonovine)
oral midazolam
Lomatide
pimozide
Saquinavir
“statin” cholesterol-lowering medicines (e.g. lovestatin, simvastatin)
Terfenadine
Tigragrelor
What kind of side effects could be a possibility from this medication?
A variety of medications can trigger negative side negative effects. A side effect is a negative reaction to a medication when used in the normal dosage. The effects may be mild or serious, and can be either temporary or lasting.
The following side effects do not affect everyone who uses this medication. Should you be concerned by the potential for side adverse effects, talk about the risks and advantages of this medication with your doctor.
The following adverse effects were reported to at minimum one percent of those taking this drug. A lot of these side effects are treatable however some might disappear on their own with time.
Talk to your doctor if have these symptoms and they’re severe or uncomfortable. Your pharmacist could be able to provide advice on how to manage adverse effects.
Abdominal discomfort
changes in the sense of the sense of
diarrhea (mild)
dizziness
gas
headache
hearing trouble
heartburn
nausea
Ringing in the ears
vomiting
While most of the adverse consequences listed below aren’t seen often, they could result in serious health issues should you not seek medical treatment.
Consult your physician promptly should any of the following reactions occur:
severe stomach or abdominal cramps and severe stomach or abdominal cramps and
skin rash
symptoms of liver disorders (e.g. abdominal tenderness the appearance of eyes that are yellow or itching or dark urine)
Myasthenia gravis symptoms (e.g. muscles weakening eyeslid drooping visual changes, difficulties swallowing and chewing, and trouble breathing)
Watery and severe diarrhea that could also be bloody
Stop taking the medicine and seek medical attention right away If one of the following occurs:
Heartbeats that are irregular or irregular
signs of an extreme allergy (e.g. the hives, itching trouble breathing, sore throat as well as swelling or redness of the mouth, face tongue, throat, or face)
signs of a severe skin reaction (e.g. peeling, peeling or blistered skin)
Certain people might have side effects that are not the ones mentioned. Talk to your doctor when you experience any symptom that you are concerned about while taking this medication.
Are there other precautions or warnings regarding this medication?
Before beginning to use any medication, you should be certain to inform your physician of any allergies or medical conditions that you may be suffering from or are taking, whether or not you are breastfeeding or pregnant, and any other important information about your health. These things can impact the way you use the medication.
Abnormal heart rhythms: Clarithromycin may cause a heart rhythm problem known as QT prolongation. If you’ve had an earlier previous history of QT prolongation, have a medical condition that is associated with QT prolongation or are taking any of the medication (e.g. amodarone or sotalol) talk to your physician about what this medication could do to the medical conditions you suffer from, and how your medical condition could influence the dosage and effectiveness of this drug, and whether you need any additional monitoring.
Allergies: If you’ve experienced an allergic reaction to azithromycin or erythromycin it is possible that you are more likely to experience some sort of reaction that is allergic to this drug. If you notice signs associated with an allergic reaction, such as a rash, consult your physician. If you experience hives; difficulty breathing, or swelling of your throat, face or tongue, you should discontinue taking the medication immediately and seek immediate medical attention.
Resistance to Bacterials: The misuse of an antibiotic , such as clarithromycin can lead to the development of resistant bacteria which will not be destroyed through the treatment. If this occurs then the antibiotic might not be effective for you in the near future. Although you may feel better after you begin taking clarithromycin. However however, you must continue taking the medication precisely as directed by your physician, to complete the process of ridding your body of infection and to stop resistance-forming bacteria from taking over. Avoid taking clarithromycin and other antibiotics to treat viral infections like the common cold. Antibiotics are not able to kill viruses and taking them to treat viral infections could result in the development in resistant bacteria.
Diarrrhea: Similar to other antibiotics, clarithromycin can be linked to a serious illness known as Clostridium-associated diarrhea due to the microorganism C. difficile. This may occur as long as 2 months following your most recent dose of this drug.
If you experience loose, watery bowel movements, particularly if they’re stinky, green or bloody and are associated with fever, whether following or during the course of taking clarithromycin, seek medical care as soon as is possible.
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Disorientation, confusion and disorientation: This medication can cause dizziness confusion or disorientation. Don’t operate or drive machinery until you’re certain that the medication will not hinder your ability to perform these tasks safely.
Kidney function kidney function kidney function could result in this medication building within the body, leading to negative side negative effects. If you are suffering from reduced kidney function, consult your doctor about how this medication could impact any medical issue, and how your medical condition might influence the dosage and effectiveness the medication. Also, discuss if you require any specific monitoring.
Liver issues: Liver diseases or a reduced function of the liver could result in this medication building up within the body, leading to adverse consequences. If you suffer from a decreased liver function, talk to your doctor about how this medication could influence the medical conditions you suffer from, and how your medical condition might influence the dosage and effectiveness that this drug has, as well as if you require any specific monitoring. This medication is not recommended for those with liver issues.
If you experience symptoms of liver issues (e.g. hunger loss nausea vomiting, discoloration of the skin or eyes blood, the appearance of dark urine or achy skin and abdominal discomfort) consult your physician immediately.
Myasthenia gravis: This drug may cause or exacerbate symptoms of myasthenia graveis. If your symptoms become more severe or you experience new symptoms such as double vision weakening of the muscles, drooping eyes or trouble chewing or swallowing, talk to your physician.
Women who are pregnant: Clarithromycin should not be taken during pregnancy, particularly during the first three months , or until an alternative therapy that is appropriate. If you fall pregnant while using this medication, consult your physician.
The medication is passed through the breast milk. If you’re a breastfeeding mother and taking clarithromycin, it could affect your infant. Discuss with your doctor whether it is safe to continue breastfeeding.
Children Safety and efficacy of clarithromycin oral suspension has not been proven for infants younger than six months old. In the case of pneumonia clarithromycin suspensions has not been examined for children less than three years old. The safety and efficacy of using clarithromycin for preventing MAC infection have not been examined for children less that 20-months old. The safety and efficacy of taking clarithromycin tablets has been questioned for children who are younger than 12 years old.